lotri: A Simple Way to Specify Symmetric, Block Diagonal Matrices
Provides a simple mechanism to specify a symmetric block diagonal matrices (often used for covariance matrices). This is based on the domain specific language implemented in 'nlmixr2' but expanded to create matrices in R generally instead of specifying parts of matrices to estimate. It has expanded to include some matrix manipulation functions that are generally useful for 'rxode2' and 'nlmixr2'.
| Version: | 1.0.3 |
| Depends: | R (≥ 3.4.0) |
| Imports: | checkmate, crayon, methods, stats, utils |
| LinkingTo: | cpp4r, armadillo4r |
| Suggests: | ggplot2, knitr, Matrix, microbenchmark, rmarkdown, testthat |
| Published: | 2026-03-11 |
| DOI: | 10.32614/CRAN.package.lotri |
| Author: | Matthew L. Fidler 
[aut, cre],
Mauricio Vargas Sepulveda
[ctb],
Bill Denney [ctb] |
| Maintainer: | Matthew L. Fidler <matthew.fidler at gmail.com> |
| BugReports: | https://github.com/nlmixr2/lotri/issues |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| URL: | https://nlmixr2.github.io/lotri/, https://github.com/nlmixr2/lotri |
| NeedsCompilation: | yes |
| Language: | en-US |
| Materials: | README, NEWS |
| CRAN checks: | lotri results |
Documentation:
| Reference manual: | lotri.html , lotri.pdf |
| Vignettes: |
Lotri Motivation (source, R code) |
Downloads:
| Package source: | lotri_1.0.3.tar.gz |
| Windows binaries: | r-devel: lotri_1.0.3.zip, r-release: lotri_1.0.2.zip, r-oldrel: lotri_1.0.3.zip |
| macOS binaries: | r-release (arm64): lotri_1.0.3.tgz, r-oldrel (arm64): lotri_1.0.3.tgz, r-release (x86_64): lotri_1.0.3.tgz, r-oldrel (x86_64): lotri_1.0.3.tgz |
| Old sources: | lotri archive |
Reverse dependencies:
| Reverse imports: | babelmixr2, monolix2rx, nlmixr2, nlmixr2est, nlmixr2extra, nonmem2rx, rxode2 |
| Reverse linking to: | nlmixr2est, rxode2 |
| Reverse suggests: | posologyr |
Linking:
Please use the canonical form https://CRAN.R-project.org/package=lotri to link to this page.