The ToxCast Data Analysis Pipeline ('tcpl') is an R package that manages, curve-fits, plots, and stores ToxCast data to populate its linked MySQL database, 'invitrodb'. The package was developed for the chemical screening data curated by the US EPA's Toxicity Forecaster (ToxCast) program, but 'tcpl' can be used to support diverse chemical screening efforts.
| Version: | 3.3.1 |
| Depends: | R (≥ 4.1.0) |
| Imports: | data.table (≥ 1.15.0), DBI, RMariaDB, numDeriv, RColorBrewer, utils, stats, methods, graphics, grDevices, sqldf, dplyr, tidyr, plotly, tcplfit2, ggplot2 (≥ 3.5.2), gridExtra, stringr, rlang, ctxR (≥ 1.1.3), viridis, gt |
| Suggests: | roxygen2, knitr, prettydoc, rmarkdown, htmlTable, testthat (≥ 3.0.0), reshape2, kableExtra, colorspace, magrittr, vdiffr, httptest, rmdformats, gtable |
| Published: | 2025-10-17 |
| DOI: | 10.32614/CRAN.package.tcpl |
| Author: | Dayne L Filer [aut],
Jason Brown |
| Maintainer: | Madison Feshuk <feshuk.madison at epa.gov> |
| BugReports: | https://github.com/USEPA/CompTox-ToxCast-tcpl/issues |
| License: | MIT + file LICENSE |
| URL: | https://github.com/USEPA/CompTox-ToxCast-tcpl, https://www.epa.gov/comptox-tools/toxicity-forecasting-toxcast |
| NeedsCompilation: | no |
| Materials: | README, NEWS |
| CRAN checks: | tcpl results |
| Reference manual: | tcpl.html , tcpl.pdf |
| Vignettes: |
1. Introduction to tcpl and invitrodb (source, R code) |
| Package source: | tcpl_3.3.1.tar.gz |
| Windows binaries: | r-devel: tcpl_3.3.1.zip, r-release: tcpl_3.3.1.zip, r-oldrel: tcpl_3.3.1.zip |
| macOS binaries: | r-release (arm64): tcpl_3.3.1.tgz, r-oldrel (arm64): tcpl_3.3.1.tgz, r-release (x86_64): tcpl_3.3.1.tgz, r-oldrel (x86_64): tcpl_3.3.1.tgz |
| Old sources: | tcpl archive |
| Reverse suggests: | Rcurvep, tcplfit2, toxEval |
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