Various semiparametric and nonparametric statistical tools for immune correlates analysis of vaccine clinical trial data. This includes calculation of summary statistics and estimation of risk, vaccine efficacy, controlled effects (controlled risk and controlled vaccine efficacy), and mediation effects (natural direct effect, natural indirect effect, proportion mediated). See Gilbert P, Fong Y, Kenny A, and Carone, M (2022) <doi:10.1093/biostatistics/kxac024> and Fay MP and Follmann DA (2023) <doi:10.48550/arXiv.2208.06465>.
| Version: | 1.3.1 |
| Depends: | R (≥ 2.10) |
| Imports: | dplyr (≥ 1.0.10), fdrtool (≥ 1.2.17), ggplot2 (≥ 3.4.0), ggpubr (≥ 0.5.0), methods (≥ 4.2.2), rlang (≥ 1.0.6), Rsolnp (≥ 1.16), splines (≥ 4.2.2), stats (≥ 4.2.2), SuperLearner (≥ 2.0.28), survival (≥ 3.4.0), survML (≥ 0.0.0.9000), truncnorm (≥ 1.0.8), e1071 (≥ 1.7.12), gam (≥ 1.22.3), ranger (≥ 0.14.0), utils (≥ 4.3.2) |
| Suggests: | knitr, rmarkdown, testthat (≥ 3.0.0) |
| Published: | 2025-09-07 |
| DOI: | 10.32614/CRAN.package.vaccine |
| Author: | Avi Kenny [aut, cre] |
| Maintainer: | Avi Kenny <avi.kenny at gmail.com> |
| BugReports: | https://github.com/Avi-Kenny/vaccine/issues |
| License: | GPL-3 |
| URL: | https://avi-kenny.github.io/vaccine/ |
| NeedsCompilation: | no |
| Materials: | README, NEWS |
| CRAN checks: | vaccine results |
| Reference manual: | vaccine.html , vaccine.pdf |
| Vignettes: |
Basic package workflow (source, R code) |
| Package source: | vaccine_1.3.1.tar.gz |
| Windows binaries: | r-devel: vaccine_1.3.1.zip, r-release: vaccine_1.3.1.zip, r-oldrel: vaccine_1.3.1.zip |
| macOS binaries: | r-release (arm64): vaccine_1.3.1.tgz, r-oldrel (arm64): vaccine_1.3.1.tgz, r-release (x86_64): vaccine_1.3.1.tgz, r-oldrel (x86_64): vaccine_1.3.1.tgz |
| Old sources: | vaccine archive |
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