Reversion mutations are secondary mutations that reverse the deleterious effects of an original pathogenic mutation, partially or fully restoring the gene's function. The revert package detects reversion mutations for a specific pathogenic mutation from DNA-seq bam files.
| Version: | 1.0.0 |
| Depends: | R (≥ 4.4.0) |
| Imports: | BSgenome, BiocGenerics, Biostrings, GenomeInfoDb, GenomicRanges, IRanges, Rsamtools, S4Vectors, ensembldb, pwalign, stats, utils |
| Suggests: | knitr, rmarkdown, futile.logger, BSgenome.Hsapiens.UCSC.hg19, EnsDb.Hsapiens.v75, BSgenome.Hsapiens.UCSC.hg38, EnsDb.Hsapiens.v86 |
| Published: | 2025-12-17 |
| DOI: | 10.32614/CRAN.package.revert |
| Author: | Hui Xiao [aut, cre], Stephen Pettitt [aut], Syed Haider [aut] |
| Maintainer: | Hui Xiao <hui.xiao at icr.ac.uk> |
| License: | GPL-2 |
| NeedsCompilation: | no |
| Materials: | NEWS |
| CRAN checks: | revert results |
| Reference manual: | revert.html , revert.pdf |
| Vignettes: |
help (source, R code) |
| Package source: | revert_1.0.0.tar.gz |
| Windows binaries: | r-devel: revert_1.0.0.zip, r-release: revert_1.0.0.zip, r-oldrel: revert_1.0.0.zip |
| macOS binaries: | r-release (arm64): revert_1.0.0.tgz, r-oldrel (arm64): revert_1.0.0.tgz, r-release (x86_64): revert_1.0.0.tgz, r-oldrel (x86_64): not available |
| Old sources: | revert archive |
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