This shows how 'NONMEM' (Beal SL, Sheiner LB, Boeckmann AJ, Bauer RJ. NONMEM 7.5 Users Guides. Icon plc, 2020) software works. 'NONMEM' classical estimation methods such as 'First Order (FO) approximation', 'First Order Conditional Estimation (FOCE)', and 'Laplacian approximation' are explained. Functions are also provided for post-run processing of NONMEM output files, generating PDF diagnostic reports including objective function value analysis, parameter estimates, prediction and residual diagnostics, empirical Bayes estimate (EBE) analysis, input data summary, and individual pharmacokinetic parameter distributions. Helper utilities for building NONMEM-ready datasets from SDTM-style source tables are also included.
| Version: | 0.3.1 |
| Depends: | R (≥ 3.5.0), numDeriv |
| Imports: | MASS, grDevices, graphics, stats, utils |
| Suggests: | testthat (≥ 3.0.0) |
| Published: | 2026-06-09 |
| DOI: | 10.32614/CRAN.package.nmw |
| Author: | Kyun-Seop Bae [aut, cre] |
| Maintainer: | Kyun-Seop Bae <k at acr.kr> |
| Contact: | Kyun-Seop Bae <k@acr.kr> |
| License: | GPL-3 |
| Copyright: | 2017-, Kyun-Seop Bae |
| URL: | https://cran.r-project.org/package=nmw |
| NeedsCompilation: | no |
| Materials: | NEWS |
| In views: | Pharmacokinetics |
| CRAN checks: | nmw results |
| Reference manual: | nmw.html , nmw.pdf |
| Package source: | nmw_0.3.1.tar.gz |
| Windows binaries: | r-devel: nmw_0.3.1.zip, r-release: nmw_0.3.0.zip, r-oldrel: nmw_0.3.1.zip |
| macOS binaries: | r-release (arm64): nmw_0.3.1.tgz, r-oldrel (arm64): nmw_0.3.1.tgz, r-release (x86_64): nmw_0.3.1.tgz, r-oldrel (x86_64): nmw_0.3.1.tgz |
| Old sources: | nmw archive |
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