Analysis of DNA copy number in single cells using custom genome-wide targeted DNA sequencing panels for the Mission Bio Tapestri platform. Users can easily parse, manipulate, and visualize datasets produced from the automated 'Tapestri Pipeline', with support for normalization, clustering, and copy number calling. Functions are also available to deconvolute multiplexed samples by genotype and parsing barcoded reads from exogenous lentiviral constructs.
| Version: | 1.0.2 |
| Depends: | R (≥ 4.1), SingleCellExperiment |
| Imports: | circlize, cli, ComplexHeatmap, dbscan, dplyr, fitdistrplus, GenomeInfoDb, GenomicRanges, ggplot2, gtools, IRanges, magrittr, methods, purrr, rhdf5, rlang, S4Vectors, stats, SummarizedExperiment, tibble, tidyr, umap, viridisLite |
| Suggests: | Biostrings, knitr, rmarkdown, Rsamtools, testthat (≥ 3.0.0) |
| Published: | 2025-11-01 |
| DOI: | 10.32614/CRAN.package.karyotapR |
| Author: | Joseph Mays |
| Maintainer: | Joseph Mays <josephcmays at gmail.com> |
| BugReports: | https://github.com/joeymays/karyotapR/issues |
| License: | MIT + file LICENSE |
| URL: | https://github.com/joeymays/karyotapR, http://joeymays.xyz/karyotapR/ |
| NeedsCompilation: | no |
| Materials: | README, NEWS |
| CRAN checks: | karyotapR results |
| Reference manual: | karyotapR.html , karyotapR.pdf |
| Package source: | karyotapR_1.0.2.tar.gz |
| Windows binaries: | r-devel: karyotapR_1.0.2.zip, r-release: karyotapR_1.0.2.zip, r-oldrel: karyotapR_1.0.2.zip |
| macOS binaries: | r-release (arm64): karyotapR_1.0.2.tgz, r-oldrel (arm64): karyotapR_1.0.2.tgz, r-release (x86_64): karyotapR_1.0.2.tgz, r-oldrel (x86_64): karyotapR_1.0.2.tgz |
| Old sources: | karyotapR archive |
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