immunogenetr: A Comprehensive Toolkit for Clinical HLA Informatics

A comprehensive toolkit for clinical Human Leukocyte Antigen (HLA) informatics, built on 'tidyverse' <https://tidyverse.tidyverse.org/> principles and making use of genotype list string (GL string, Mack et al. (2023) <doi:10.1111/tan.15126>) for storing and computing HLA genotype data. Specific functionalities include: coercion of HLA data in tabular format to and from GL string; calculation of matching and mismatching in all directions, with multiple output formats; automatic formatting of HLA data for searching within a GL string; truncation of molecular HLA data to a specific number of fields; and reading HLA genotypes in HML files and extracting the GL string. This library is intended for research use. Any application making use of this package in a clinical setting will need to be independently validated according to local regulations.

Version:	1.0.1
Depends:	R (≥ 4.1.0)
Imports:	cli (≥ 1.0.0), dplyr (≥ 1.1.1), glue (≥ 1.8.0), magrittr (≥ 2.0.3), purrr (≥ 1.0.2), rlang (≥ 1.1.2), stringr (≥ 1.5.0), tibble (≥ 3.1.3), tidyr (≥ 1.3.0), tidyselect (≥ 1.2.0), xml2 (≥ 1.3.6)
Suggests:	testthat (≥ 3.0.0)
Published:	2025-10-23
DOI:	10.32614/CRAN.package.immunogenetr
Author:	Nicholas Brown [cre, aut], Busra Coskun [aut]
Maintainer:	Nicholas Brown <nicholas.brown at pennmedicine.upenn.edu>
BugReports:	https://github.com/k96nb01/immunogenetr_package/issues
License:	GPL (≥ 3)
URL:	https://github.com/k96nb01/immunogenetr_package
NeedsCompilation:	no
Language:	en-US
Materials:	README, NEWS
CRAN checks:	immunogenetr results

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