gprofiler2: Interface to the 'g:Profiler' Toolset

A toolset for functional enrichment analysis and visualization, gene/protein/SNP identifier conversion and mapping orthologous genes across species via 'g:Profiler' (<https://biit.cs.ut.ee/gprofiler/>). The main tools are: (1) 'g:GOSt' - functional enrichment analysis and visualization of gene lists; (2) 'g:Convert' - gene/protein/transcript identifier conversion across various namespaces; (3) 'g:Orth' - orthology search across species; (4) 'g:SNPense' - mapping SNP rs identifiers to chromosome positions, genes and variant effects. This package is an R interface corresponding to the 2019 update of 'g:Profiler' and provides access to 'g:Profiler' for versions 'e94_eg41_p11' and higher. See the package 'gProfileR' for accessing older versions from the 'g:Profiler' toolset.

Version:	0.2.4
Depends:	R (≥ 3.5)
Imports:	jsonlite, RCurl, ggplot2, plotly, tidyr (≥ 1.0.0), crosstalk, grDevices, gridExtra, grid, viridisLite, dplyr, curl
Suggests:	knitr, rmarkdown, prettydoc
Published:	2025-11-11
DOI:	10.32614/CRAN.package.gprofiler2
Author:	Liis Kolberg [aut, cre], Uku Raudvere [aut]
Maintainer:	Liis Kolberg <liis.kolberg at ut.ee>
BugReports:	https://biit.cs.ut.ee/gprofiler/page/contact
License:	GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation:	no
Citation:	gprofiler2 citation info
In views:	Omics
CRAN checks:	gprofiler2 results

Documentation:

Reference manual:	gprofiler2.html , gprofiler2.pdf
Vignettes:	gprofiler2 (source, R code)

Downloads:

Package source:	gprofiler2_0.2.4.tar.gz
Windows binaries:	r-devel: gprofiler2_0.2.4.zip, r-release: gprofiler2_0.2.4.zip, r-oldrel: gprofiler2_0.2.4.zip
macOS binaries:	r-release (arm64): gprofiler2_0.2.4.tgz, r-oldrel (arm64): gprofiler2_0.2.4.tgz, r-release (x86_64): gprofiler2_0.2.4.tgz, r-oldrel (x86_64): gprofiler2_0.2.4.tgz
Old sources:	gprofiler2 archive

Reverse dependencies:

Reverse imports:	annotaR, ClustAssess, DFD, enrichViewNet, famat, GWENA, MultiRNAflow, orthogene, PRONE, RCAS, scMappR, UniprotR, XYomics
Reverse suggests:	clustifyr, HPiP, knowYourCG, OmnipathR, rliger, scLANE

Linking:

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