dotgen: Gene-Set Analysis via Decorrelation by Orthogonal Transformation
Decorrelates a set of summary statistics (i.e., Z-scores or P-values per SNP) via Decorrelation by Orthogonal Transformation (DOT) approach and performs gene-set analyses by combining transformed statistic values; operations are performed with algorithms that rely only on the association summary results and the linkage disequilibrium (LD). For more details on DOT and its power, see Olga (2020) <doi:10.1371/journal.pcbi.1007819>.
| Version: | 0.1.1 |
| Depends: | R (≥ 3.5.0), mvtnorm |
| Published: | 2024-10-27 |
| DOI: | 10.32614/CRAN.package.dotgen |
| Author: | Olga Vsevolozhskaya
 [aut],
Dmitri Zaykin
[aut],
Xiaoran Tong
[aut, cre] |
| Maintainer: | Xiaoran Tong <xt at uky.edu> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| URL: | https://github.com/xiaoran831213/dotgen |
| NeedsCompilation: | no |
| CRAN checks: | dotgen results |
Documentation:
| Reference manual: | dotgen.html , dotgen.pdf |
Downloads:
| Package source: | dotgen_0.1.1.tar.gz |
| Windows binaries: | r-devel: dotgen_0.1.1.zip, r-release: dotgen_0.1.1.zip, r-oldrel: dotgen_0.1.1.zip |
| macOS binaries: | r-release (arm64): dotgen_0.1.1.tgz, r-oldrel (arm64): dotgen_0.1.1.tgz, r-release (x86_64): dotgen_0.1.1.tgz, r-oldrel (x86_64): dotgen_0.1.1.tgz |
| Old sources: | dotgen archive |
Linking:
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