aNCA: (Pre-)Clinical NCA in a Dynamic Shiny App

An interactive 'shiny' application for performing non-compartmental analysis (NCA) on pre-clinical and clinical pharmacokinetic data. The package builds on 'PKNCA' for core estimators and provides interactive visualizations, CDISC outputs ('ADNCA', 'PP', 'ADPP') and configurable TLGs (tables, listings, and graphs). Typical use cases include exploratory analysis, validation, reporting or teaching/demonstration of NCA methods. Methods and core estimators are described in Denney, Duvvuri, and Buckeridge (2015) "Simple, Automatic Noncompartmental Analysis: The PKNCA R Package" <doi:10.1007/s10928-015-9432-2>.

Version:	0.1.0
Depends:	R (≥ 4.1)
Imports:	dplyr, formatters, flextable, ggplot2, magrittr, methods, officer, PKNCA (≥ 0.12.1), plotly, purrr, rlang, rlistings, scales, stats, stringr, tern, tidyr, units, utils
Suggests:	arrow, covr, DT, ggh4x, glue, haven, htmltools, htmlwidgets, jsonlite, knitr, lintr (≥ 3.1.2), logger, markdown, mockery, nestcolor, openxlsx2, pak, reactable, reactable.extras, rmarkdown, sass, shiny, shinycssloaders, shinyjs, shinyjqui, shinytest2, shinyWidgets, stringi, testthat (≥ 3.0.0), tools, quarto, vdiffr, withr, yaml
Published:	2025-12-09
DOI:	10.32614/CRAN.package.aNCA
Author:	Ercan Suekuer [aut], Gerardo Jose Rodriguez [aut], Pascal Baertschi [aut], Jana Spinner [aut], Mateusz Kolomanski [aut], Lucy Aspridis [aut], Valentin Legras [aut, cre], F. Hoffmann-La Roche AG [cph, fnd]
Maintainer:	Valentin Legras <anca.pharmaverse at gmail.com>
BugReports:	https://github.com/pharmaverse/aNCA/issues
License:	Apache License (≥ 2)
URL:	https://pharmaverse.github.io/aNCA/, https://github.com/pharmaverse/aNCA
NeedsCompilation:	no
Language:	en-US
Materials:	README
CRAN checks:	aNCA results

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