Calibrates Bayesian two-stage designs for single-arm phase II trials with time-to-event endpoints using a window-cohort with controlled roll-on. Interim monitoring is anchored to a locked interim cohort and a pre-specified follow-up requirement, so analysis timing remains predictable while preserving follow-up maturity. The package searches feasible interim rules, optimizes final sample size and decision thresholds, evaluates operating characteristics by Monte Carlo simulation, and supports exponential, Weibull, log-normal, log-logistic, and user-defined baseline survival models. Related published foundations include Simon (1989) <doi:10.1016/0197-2456(89)90015-9> and Cotterill and Whitehead (2015) <doi:10.1002/sim.6426>.
| Version: | 1.0.1 |
| Depends: | R (≥ 4.4.0) |
| Imports: | foreach, doParallel, stats, parallel |
| Suggests: | devtools, roxygen2, knitr, rmarkdown, testthat (≥ 3.0.0) |
| Published: | 2026-04-10 |
| DOI: | 10.32614/CRAN.package.WCRBayesDesign |
| Author: | Zhongheng Cai [aut, cre], Haitao Pan [aut] |
| Maintainer: | Zhongheng Cai <zhonghengcai123 at gmail.com> |
| License: | GPL-3 |
| NeedsCompilation: | no |
| Materials: | README |
| CRAN checks: | WCRBayesDesign results |
| Reference manual: | WCRBayesDesign.html , WCRBayesDesign.pdf |
| Package source: | WCRBayesDesign_1.0.1.tar.gz |
| Windows binaries: | r-devel: WCRBayesDesign_1.0.1.zip, r-release: WCRBayesDesign_1.0.1.zip, r-oldrel: WCRBayesDesign_1.0.1.zip |
| macOS binaries: | r-release (arm64): WCRBayesDesign_1.0.1.tgz, r-oldrel (arm64): WCRBayesDesign_1.0.1.tgz, r-release (x86_64): WCRBayesDesign_1.0.1.tgz, r-oldrel (x86_64): WCRBayesDesign_1.0.1.tgz |
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