Provides a unified workflow for building, fitting using external engines, and evaluating ordinary differential equation (ODE)-based pharmacokinetic/pharmacodynamic (PK/PD) models. Supports generation of estimation scenarios and control files for external engines (e.g., 'Monolix'), simulation of models using 'rxode2', and creation of goodness-of-fit diagnostics. Includes tools for covariate modeling, virtual population design, and local and global sensitivity analyses.
| Version: | 0.2.0 |
| Depends: | R (≥ 3.5) |
| Imports: | cluster, dplyr, fastDummies, forcats, ggplot2, jsonlite, MASS, philentropy, purrr, readr, recipes, rlang, rxode2, scales, stringr, synthpop, sys, tibble, tidyr, uwot, zoo, lhs, sensitivity, ppcor, withr |
| Suggests: | GGally, testthat (≥ 3.0.0) |
| Published: | 2026-05-19 |
| DOI: | 10.32614/CRAN.package.SimuRg (may not be active yet) |
| Author: | Victor Sokolov [cph, aut], Anna Mikhailova [cre], Yaroslav Ugolkov [aut], Anatoly Pokladyuk [aut], Alina Melnikova [aut], Victoria Kulesh [aut] |
| Maintainer: | Anna Mikhailova <anna.mikhailova at msdecisions.tech> |
| License: | MIT + file LICENSE |
| NeedsCompilation: | no |
| Materials: | README, NEWS |
| CRAN checks: | SimuRg results |
| Reference manual: | SimuRg.html , SimuRg.pdf |
| Package source: | SimuRg_0.2.0.tar.gz |
| Windows binaries: | r-devel: not available, r-release: SimuRg_0.2.0.zip, r-oldrel: SimuRg_0.2.0.zip |
| macOS binaries: | r-release (arm64): SimuRg_0.2.0.tgz, r-oldrel (arm64): SimuRg_0.2.0.tgz, r-release (x86_64): SimuRg_0.2.0.tgz, r-oldrel (x86_64): SimuRg_0.2.0.tgz |
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