Some response-adaptive randomization methods commonly found in literature are included in this package. These methods include the randomized play-the-winner rule for binary endpoint (Wei and Durham (1978) <doi:10.2307/2286290>), the doubly adaptive biased coin design with minimal variance strategy for binary endpoint (Atkinson and Biswas (2013) <doi:10.1201/b16101>, Rosenberger and Lachin (2015) <doi:10.1002/9781118742112>) and maximal power strategy targeting Neyman allocation for binary endpoint (Tymofyeyev, Rosenberger, and Hu (2007) <doi:10.1198/016214506000000906>) and RSIHR allocation with each letter representing the first character of the names of the individuals who first proposed this rule (Youngsook and Hu (2010) <doi:10.1198/sbr.2009.0056>, Bello and Sabo (2016) <doi:10.1080/00949655.2015.1114116>), A-optimal Allocation for continuous endpoint (Sverdlov and Rosenberger (2013) <doi:10.1080/15598608.2013.783726>), Aa-optimal Allocation for continuous endpoint (Sverdlov and Rosenberger (2013) <doi:10.1080/15598608.2013.783726>), generalized RSIHR allocation for continuous endpoint (Atkinson and Biswas (2013) <doi:10.1201/b16101>), Bayesian response-adaptive randomization with a control group using the Thall \& Wathen method for binary and continuous endpoints (Thall and Wathen (2007) <doi:10.1016/j.ejca.2007.01.006>) and the forward-looking Gittins index rule for binary and continuous endpoints (Villar, Wason, and Bowden (2015) <doi:10.1111/biom.12337>, Williamson and Villar (2019) <doi:10.1111/biom.13119>).
| Version: | 0.0.2 |
| Depends: | R (≥ 4.3), stats, pins |
| Imports: | Rdpack (≥ 0.7) |
| Suggests: | knitr, rmarkdown, testthat (≥ 3.0.0) |
| Published: | 2025-04-03 |
| DOI: | 10.32614/CRAN.package.RARtrials |
| Author: | Chuyao Xu [aut, cre], Thomas Lumley [aut, ths], Alain Vandal [aut, ths], Sofia S. Villar [cph], Kyle J. Wathen [cph] |
| Maintainer: | Chuyao Xu <cxu870 at aucklanduni.ac.nz> |
| License: | GPL (≥ 3) |
| URL: | https://github.com/yayayaoyaoyao/RARtrials |
| NeedsCompilation: | no |
| Materials: | README |
| CRAN checks: | RARtrials results |
| Reference manual: | RARtrials.html , RARtrials.pdf |
| Vignettes: |
Response-Adaptive randomization in Clinical Trials (source, R code) |
| Package source: | RARtrials_0.0.2.tar.gz |
| Windows binaries: | r-devel: RARtrials_0.0.2.zip, r-release: RARtrials_0.0.2.zip, r-oldrel: RARtrials_0.0.2.zip |
| macOS binaries: | r-release (arm64): RARtrials_0.0.2.tgz, r-oldrel (arm64): RARtrials_0.0.2.tgz, r-release (x86_64): RARtrials_0.0.2.tgz, r-oldrel (x86_64): RARtrials_0.0.2.tgz |
| Old sources: | RARtrials archive |
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