ParCC (Parameter Converter & Calculator) provides a comprehensive set of tutorials organized by topic. Each vignette includes realistic clinical scenarios, worked examples with R code, and references to the underlying methodology.
vignette("getting-started") –
Installation, launching the app, and the Lab Notebook workflowvignette("core-conversions") – Rate to
Probability, Odds to Probability, and Time Rescaling with real-world
examples from the RE-LY trial and UKPDS Risk Enginevignette("hr-probability-converter") –
Converting control group probabilities to intervention probabilities
using Hazard Ratios. Includes worked examples from the PLATO trial
(Ticagrelor vs Aspirin) and oncology models.vignette("survival-extrapolation") –
Fitting Exponential and Weibull survival curves from published
Kaplan-Meier data when IPD is unavailablevignette("background-mortality") – SMR
adjustment, DEALE, Gompertz parameterization, and linear interpolation
for adjusting census life tables to disease-specific cohortsvignette("psa-distributions") –
Fitting Beta (utilities), Gamma (costs), and LogNormal (HRs)
distributions using the Method of Moments. Includes the Rule of 4
approximation.vignette("economic-evaluation") – ICER
calculation, Net Monetary Benefit, and Value-Based Pricing (Headroom
Analysis) with Indian HTA contextvignette("batch-workflow") – Uploading
CSV files for bulk conversion, including the new HR-based batch
conversion
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