PERSUADE: Parametric Survival Model Selection for Decision-Analytic Models
Provides a standardized framework to support the selection
and evaluation of parametric survival models for time-to-event data.
Includes tools for visualizing survival data, checking proportional
hazards assumptions (Grambsch and Therneau, 1994,
<doi:10.1093/biomet/81.3.515>), comparing parametric (Ishak and
colleagues, 2013, <doi:10.1007/s40273-013-0064-3>), spline (Royston
and Parmar, 2002, <doi:10.1002/sim.1203>) and cure models, examining
hazard functions, and evaluating model extrapolation. Methods are
consistent with recommendations in the NICE Decision Support Unit
Technical Support Documents (14 and 21
<https://sheffield.ac.uk/nice-dsu/tsds/survival-analysis>). Results
are structured to facilitate integration into decision-analytic
models, and reports can be generated with 'rmarkdown'. The package
builds on existing tools including 'flexsurv' (Jackson, 2016,
<doi:10.18637/jss.v070.i08>)) and 'flexsurvcure' for estimating cure
models.
| Version: |
0.1.2 |
| Depends: |
R (≥ 4.1.0) |
| Imports: |
data.table, flexsurv, flexsurvcure, ggplot2, muhaz, rmarkdown, rms, sft, stats, survival, survminer |
| Suggests: |
kableExtra, knitr, testthat (≥ 3.1.2), utils |
| Published: |
2025-10-09 |
| DOI: |
10.32614/CRAN.package.PERSUADE |
| Author: |
Bram Ramaekers 
[aut, cre, ths],
Xavier Pouwels
[ctb],
Sabine Grimm
[ths],
Manuela Joore
[ths] |
| Maintainer: |
Bram Ramaekers <bram.ramaekers at mumc.nl> |
| BugReports: |
https://github.com/Bram-R/PERSUADE/issues |
| License: |
GPL (≥ 3) |
| URL: |
https://github.com/Bram-R/PERSUADE |
| NeedsCompilation: |
no |
| Materials: |
README, NEWS |
| CRAN checks: |
PERSUADE results |
Documentation:
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