NOVA 0.1.1

CRAN Resubmission Fixes

• Removed all commented code from examples and function bodies
• Fixed DESCRIPTION to spell out Multi-Electrode Array (MEA) without quotes
• Added newlines at end of all R source files
• Fixed parse errors in documentation examples

Initial CRAN Release

This is the first release of NOVA (Neuroactivity Omics Visualization and Analysis), a comprehensive toolkit for analyzing and visualizing Multi-Electrode Array (MEA) data.

Main Features

• Data Processing: Flexible MEA data processing with automatic structure discovery
  • discover_mea_structure(): Automatically detects data structure
  • process_mea_flexible(): Processes MEA data with quality filtering options
  • handle_missing_values(): Multiple strategies for handling missing data
• Principal Component Analysis:
  • pca_analysis_enhanced(): Comprehensive PCA with visualization
  • analyze_pca_variable_importance_general(): Variable importance analysis
  • plot_pca_trajectories_general(): Trajectory visualization across conditions
• Heatmap Visualization:
  • create_mea_heatmaps_enhanced(): Publication-ready heatmaps with multiple scaling options
  • Support for hierarchical clustering and custom annotations
• Utility Functions: Helper functions for data manipulation, scaling, and color schemes

Documentation

• Comprehensive function documentation with examples
• Vignettes demonstrating typical workflows
• Support for various MEA data formats