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CRAN: Package MRPC

MRPC: PC Algorithm with the Principle of Mendelian Randomization

A PC Algorithm with the Principle of Mendelian Randomization. This package implements the MRPC (PC with the principle of Mendelian randomization) algorithm to infer causal graphs. It also contains functions to simulate data under a certain topology, to visualize a graph in different ways, and to compare graphs and quantify the differences. See Badsha and Fu (2019) <doi:10.3389/fgene.2019.00460>, Badsha, Martin and Fu (2021) <doi:10.3389/fgene.2021.651812>, Kvamme and Badsha, et al. (2025) <doi:10.1093/genetics/iyaf064>.

Version: 3.2.0
Depends: R (≥ 4.0)
Imports: bnlearn, compositions, dynamicTreeCut, GGally, fastcluster, gtools, graph, graphics, Hmisc, methods, mice, network, pcalg, psych, Rgraphviz, stats, utils, WGCNA, plyr
Published: 2025-09-13
DOI: 10.32614/CRAN.package.MRPC
Author: Md Bahadur Badsha [aut], Evan A Martin [ctb], Audrey Fu [aut, cre]
Maintainer: Audrey Fu <audreyqyfu at gmail.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: no
Materials: README
In views: CausalInference
CRAN checks: MRPC results

Documentation:

Reference manual: MRPC.html , MRPC.pdf

Downloads:

Package source: MRPC_3.2.0.tar.gz
Windows binaries: r-devel: MRPC_3.2.0.zip, r-release: MRPC_3.2.0.zip, r-oldrel: MRPC_3.2.0.zip
macOS binaries: r-release (arm64): MRPC_3.2.0.tgz, r-oldrel (arm64): MRPC_3.2.0.tgz, r-release (x86_64): MRPC_3.2.0.tgz, r-oldrel (x86_64): MRPC_3.2.0.tgz
Old sources: MRPC archive

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