Cellular cooperation compromises the established method of calculating clonogenic activity from limiting dilution assay (LDA) data. This tool provides functions that enable robust analysis in presence or absence of cellular cooperation. The implemented method incorporates the same cooperativity module to model the non-linearity associated with cellular cooperation as known from the colony formation assay (Brix et al. (2021) <doi:10.1038/s41596-021-00615-0>: "Analysis of clonogenic growth in vitro." Nature protocols).
| Version: | 0.1.2 |
| Depends: | R (≥ 3.5.0) |
| Imports: | Hmisc |
| Suggests: | knitr, rmarkdown, testthat (≥ 3.0.0) |
| Published: | 2024-07-17 |
| DOI: | 10.32614/CRAN.package.LDAcoop |
| Author: | Daniel Samaga [cre, aut], Nikko Brix [aut], Benedek Danko [aut], Kirsten Lauber [aut], Horst Zitzelsberger [aut] |
| Maintainer: | Daniel Samaga <daniel.samaga at helmholtz-munich.de> |
| BugReports: | https://github.com/ZytoHMGU/LDAcoop/issues |
| License: | GPL-3 |
| URL: | https://github.com/ZytoHMGU/LDAcoop |
| NeedsCompilation: | no |
| Materials: | README |
| CRAN checks: | LDAcoop results |
| Reference manual: | LDAcoop.html , LDAcoop.pdf |
| Vignettes: |
LDAcoop (source, R code) |
| Package source: | LDAcoop_0.1.2.tar.gz |
| Windows binaries: | r-devel: LDAcoop_0.1.2.zip, r-release: LDAcoop_0.1.2.zip, r-oldrel: LDAcoop_0.1.2.zip |
| macOS binaries: | r-release (arm64): LDAcoop_0.1.2.tgz, r-oldrel (arm64): LDAcoop_0.1.2.tgz, r-release (x86_64): LDAcoop_0.1.2.tgz, r-oldrel (x86_64): LDAcoop_0.1.2.tgz |
| Old sources: | LDAcoop archive |
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