InterSIM: Simulation of Inter-Related Genomic Datasets

Generates three inter-related genomic datasets: methylation, gene expression and protein expression having user specified cluster patterns. The simulation utilizes the realistic inter- and intra- relationships from real DNA methylation, mRNA expression and protein expression data from the TCGA ovarian cancer study, Chalise (2016) <doi:10.1016/j.cmpb.2016.02.011>.

Version:	2.3.0
Depends:	R (≥ 3.5.0), MASS, NMF, tools
Published:	2025-01-10
DOI:	10.32614/CRAN.package.InterSIM
Author:	Prabhakar Chalise [aut, cre], Rama Raghavan [aut], Brooke Fridley [aut]
Maintainer:	Prabhakar Chalise <pchalise at kumc.edu>
License:	GPL-2 | GPL-3 [expanded from: GPL]
NeedsCompilation:	no
CRAN checks:	InterSIM results

Documentation:

Reference manual:

InterSIM.html , InterSIM.pdf

Downloads:

Package source:	InterSIM_2.3.0.tar.gz
Windows binaries:	r-devel: InterSIM_2.3.0.zip, r-release: InterSIM_2.3.0.zip, r-oldrel: InterSIM_2.3.0.zip
macOS binaries:	r-release (arm64): InterSIM_2.3.0.tgz, r-oldrel (arm64): InterSIM_2.3.0.tgz, r-release (x86_64): InterSIM_2.3.0.tgz, r-oldrel (x86_64): InterSIM_2.3.0.tgz
Old sources:	InterSIM archive

Reverse dependencies:

Reverse depends:	IntNMF
Reverse imports:	M3JF

Linking:

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