Computes pathway-level transcriptional disruption scores from differential expression p-values using permutation tests with Generalized Pareto Distribution (GPD) tail extrapolation and false discovery rate (FDR) correction. Reference: Guo P, Li H (2026) DSGE: Disruption Score of Gene Expression for Gene-Set Enrichment Analysis. <https://github.com/LHJLab/DSGE>.
| Version: | 1.3.1 |
| Imports: | data.table, evd, methods, POT, Rcpp |
| LinkingTo: | Rcpp |
| Suggests: | AnnotationDbi, GO.db |
| Enhances: | KEGGREST, org.Hs.eg.db, reactome.db |
| Published: | 2026-06-30 |
| DOI: | 10.32614/CRAN.package.DSGEr (may not be active yet) |
| Author: | Pingwei Guo [aut, cre], Huijuan Li [aut] |
| Maintainer: | Pingwei Guo <1489413126 at qq.com> |
| License: | MIT + file LICENSE |
| NeedsCompilation: | yes |
| Citation: | DSGEr citation info |
| Materials: | README |
| CRAN checks: | DSGEr results |
| Reference manual: | DSGEr.html , DSGEr.pdf |
| Package source: | DSGEr_1.3.1.tar.gz |
| Windows binaries: | r-devel: DSGEr_1.3.1.zip, r-release: not available, r-oldrel: DSGEr_1.3.1.zip |
| macOS binaries: | r-release (arm64): DSGEr_1.3.1.tgz, r-oldrel (arm64): DSGEr_1.3.1.tgz, r-release (x86_64): DSGEr_1.3.1.tgz, r-oldrel (x86_64): DSGEr_1.3.1.tgz |
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