An implementation of the Bayesian Surrogate Evaluation Test (BSET) for assessing the validity of surrogate markers in clinical trials. Provides hypothesis testing tools to evaluate whether a surrogate can reliably estimate the causal effect of a treatment on a primary outcome. Implements the imputation-based Bayesian methodology of Carlotti and Parast (2026) <doi:10.48550/arXiv.2603.14381>, extending the frequentist rank-based approach of Parast et al. (2024) <doi:10.1093/biomtc/ujad035>. Addresses key limitations of the frequentist method, including the lack of causal interpretability and the inability to adjust for covariates in the estimation process.
| Version: | 1.0 |
| Depends: | R (≥ 3.5) |
| Imports: | rstan, ggplot2, future, parallel, mvtnorm, dplyr, SurrogateRank, Rdpack, rlang |
| Suggests: | knitr, rmarkdown, bookdown |
| Published: | 2026-05-22 |
| DOI: | 10.32614/CRAN.package.BSET |
| Author: | Pietro Carlotti [aut, cre], Layla Parast [aut] |
| Maintainer: | Pietro Carlotti <pietro.carlotti at utexas.edu> |
| BugReports: | https://github.com/PietroCarlotti/BSET/issues |
| License: | GPL-3 |
| URL: | https://pietrocarlotti.github.io/BSET/, https://github.com/PietroCarlotti/BSET |
| NeedsCompilation: | no |
| Materials: | README |
| CRAN checks: | BSET results |
| Reference manual: | BSET.html , BSET.pdf |
| Vignettes: |
BSET Tutorial (source, R code) |
| Package source: | BSET_1.0.tar.gz |
| Windows binaries: | r-devel: BSET_1.0.zip, r-release: BSET_1.0.zip, r-oldrel: BSET_1.0.zip |
| macOS binaries: | r-release (arm64): BSET_1.0.tgz, r-oldrel (arm64): BSET_1.0.tgz, r-release (x86_64): BSET_1.0.tgz, r-oldrel (x86_64): BSET_1.0.tgz |
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