<?xml version="1.0" encoding="UTF-8"?>
<oai_dc:dc xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd">
  <dc:title>Linear Compartment Model Solutions and Gradients for 'rxode2'</dc:title>
  <dc:title>R package rxode2lincmt version 0.1.0</dc:title>
  <dc:description>Analytic one, two and three compartment linear pharmacokinetic
    solutions with their parameter gradients from 'stan' automatic
    differentiation (Carpenter et al (2015) &lt;doi:10.48550/arXiv.1509.07164&gt;),
    eigen decompositions and derived-parameter conversions used by 'rxode2'
    (Wang, Hallow and James (2016) &lt;doi:10.1002/psp4.12052&gt;).  Split out of
    'rxode2' so its installation does not compile 'stan' AD items which made it
    take too long to compile by itself.
    The closed-form solutions follow the idea of the 'wnl' package
    (Bae, &lt;https://CRAN.R-project.org/package=wnl&gt;), though the
    implementation here is different.</dc:description>
  <dc:type>Software</dc:type>
  <dc:relation>Depends: R (&gt;= 4.1.0)</dc:relation>
  <dc:relation>Imports: Rcpp (&gt;= 1.0.8), checkmate</dc:relation>
  <dc:relation>LinkingTo: Rcpp (&gt;= 1.0.8), RcppEigen (&gt;= 0.3.3.9.2), StanHeaders (&gt;=
2.21.0.7), BH, RcppParallel</dc:relation>
  <dc:relation>Suggests: covr, testthat (&gt;= 3.0.0)</dc:relation>
  <dc:creator>Matthew L. Fidler &lt;matthew.fidler@gmail.com&gt;</dc:creator>
  <dc:publisher>Comprehensive R Archive Network (CRAN)</dc:publisher>
  <dc:contributor>Matthew L. Fidler [aut, cre] (ORCID:
    &lt;https://orcid.org/0000-0001-8538-6691&gt;),
  Richard Upton [ctb]</dc:contributor>
  <dc:rights>GPL (&gt;= 3)</dc:rights>
  <dc:date>2026-09-24</dc:date>
  <dc:format>application/tgz</dc:format>
  <dc:identifier>https://CRAN.R-project.org/package=rxode2lincmt</dc:identifier>
  <dc:identifier>doi:10.32614/CRAN.package.rxode2lincmt</dc:identifier>
  <dc:language>en-US</dc:language>
</oai_dc:dc>
