A Package to Find Minimal Transcriptional Signatures R package fspls2 version 0.1.0 Identifies minimal biomarker signatures for predicting phenotypes from multiomic data. Integrates multiple omics layers, supports internal cross-validation. Supports missing values in predictors and outcomes. Enables model based imputation of uncertain values. Supports continuous, binary, multi-class and ordinal outcomes. Software Depends: R (>= 4.1.0) Imports: R6, jsonlite, Matrix, glmnet, tidyr, MASS, ggplot2, pROC, binom, confintr, DBI, RSQLite, methods,tibble, ggrepel, RColorBrewer, data.table Suggests: knitr, rmarkdown, testthat Lachlan Coin <l.coin@imb.uq.edu.au> Comprehensive R Archive Network (CRAN) Lachlan Coin [aut, cre] GPL-2 2026-09-12 application/tgz https://CRAN.R-project.org/package=fspls2 doi:10.32614/CRAN.package.fspls2