An Umbrella Framework for Multi-Source and Multi-Omics Clustering R package MosaiClusteR version 0.1.0 An umbrella framework ("MoSaIC" = Multi-Omics Source-Agnostic Integration Clustering in R) that unifies a large collection of multi-source / multi-omics clustering methodologies behind a single, consistent list-of-matrices interface. It spans five integration paradigms - direct, similarity-based, graph-based, voting-based consensus, and hierarchy-based - and bundles a complete downstream workflow for method comparison and evaluation. The package features the multi-source the ability to compare many algorithms on the same footing, a data-nugget based feature-weighting scheme as a robust, big-data-friendly alternative to variance weighting, and a downstream suite for cluster characterisation, visualisation and biological interpretation. Software Depends: R (>= 4.0) Imports: stats, utils, methods, graphics, grDevices, cluster, fastcluster, matrixStats, FD, ade4, e1071, gtools, data.table, Rcpp, Rdpack LinkingTo: Rcpp Suggests: SNFtool, datanugget, WCluster, LUCIDus, igraph, lsa, analogue, FactoMineR, pls, circlize, gplots, dendextend, plotrix, limma, MLP, biomaRt, org.Hs.eg.db, Biobase, a4Core, a4Base, plyr, genefilter, ggplot2, gridExtra, uwot, Rtsne, MOFAdata, testthat (>= 3.0.0), knitr, rmarkdown Bernard Isekah Osang'ir <bernard.osangir@sckcen.be> Comprehensive R Archive Network (CRAN) Bernard Isekah Osang'ir [aut, cre] (ORCID: <https://orcid.org/0000-0002-5557-3602>), Marijke Van Moerbeke [aut], Ziv Shkedy [ctb], Surya Gupta [ctb], Jürgen Claesen [ctb] GPL-3 2026-07-29 application/tgz https://CRAN.R-project.org/package=MosaiClusteR doi:10.32614/CRAN.package.MosaiClusteR