Transcriptional Disruption Score for Gene Sets


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Documentation for package ‘DSGEr’ version 1.3.1

Help Pages

calc_dsge Compute DSGE (Disruption Score of Gene Expression)
dsge_perm_test Permutation test for DSGE enrichment of a single gene set
get_gaf_header Extract header lines from a GAF file
get_pathway_genes Extract gene-pathway (GO term) associations from GAF data
get_pathway_genes_db Build pathway-gene mapping from a Bioconductor OrgDb object
get_pathway_genes_kegg Build KEGG pathway-gene mapping from a Bioconductor OrgDb object
get_pathway_genes_reactome Build Reactome pathway-gene mapping from a Bioconductor OrgDb object
pathway_dsge Pathway-level DSGE permutation test with FDR correction
plot_dsge Plot null distribution vs. observed DSGE for selected pathways
plot_dsge_volcano Gene-level volcano plot for a specific pathway
read_gaf Read a Gene Ontology Annotation File (GAF)
read_obo Read GO term names from an OBO file