Bayesian estimation for undirected graphical models using spike-and-slab priors. The package handles continuous, discrete, and mixed data.

Connect to a remote server over SSH to transfer files via SCP, 
    setup a secure tunnel, or run a command or script on the host while 
    streaming stdout and stderr directly to the client.

Processes amino acid alignments produced by the 'IPD-IMGT/HLA (Immuno Polymorphism-ImMunoGeneTics/Human Leukocyte Antigen) Database' to identify user-defined amino acid residue motifs shared across HLA alleles, HLA alleles, or HLA haplotypes, and calculates frequencies based on HLA allele frequency data. 'SSHAARP' (Searching Shared HLA Amino Acid Residue Prevalence) uses 'Generic Mapping Tools (GMT)' software and the 'GMT' R package to generate global frequency heat maps that illustrate the distribution of each user-defined map around the globe. 'SSHAARP' analyzes the allele frequency data described by Solberg et al. (2008) <doi:10.1016/j.humimm.2008.05.001>, a global set of 497 population samples from 185 published datasets, representing 66,800 individuals total. Users may also specify their own datasets, but file conventions must follow the prebundled Solberg dataset, or the mock haplotype dataset.

Estimation of an S-shaped function and its corresponding inflection point via a least squares approach. A sequential mixed primal-dual based algorithm is implemented for the fast computation. Details can be found in Feng et al. (2022) <doi:10.1111/rssb.12481>.

Spatial stratified heterogeneity (SSH) denotes the coexistence of within-strata homogeneity and between-strata heterogeneity. Information consistency-based methods provide a rigorous approach to quantify SSH and evaluate its role in spatial processes, grounded in principles of geographical stratification and information theory (Bai, H. et al. (2023) <doi:10.1080/24694452.2023.2223700>; Wang, J. et al. (2024) <doi:10.1080/24694452.2023.2289982>).

Convenient tools for exchanging files securely from within R. By
    encrypting the content safe passage of files (shipment) can be provided by
    common but insecure carriers such as ftp and email. Based on asymmetric
    cryptography no management of shared secrets is needed to make a secure
    shipment as long as authentic public keys are available. Public keys used
    for secure shipments may also be obtained from external providers as part of
    the overall process. Transportation of files will require that relevant
    services such as ftp and email servers are available.