One function to read files. One function to write files. One
    function to direct plots to screen or file. Automatic file format inference
    and directory structure creation.

Calculates fundamental IO matrices (Leontief, Wassily W. (1951) <doi:10.1038/scientificamerican1051-15>); within period analysis via various rankings and coefficients (Sonis and Hewings (2006) <doi:10.1080/09535319200000013>, Blair and Miller (2009) <ISBN:978-0-521-73902-3>, Antras et al (2012) <doi:10.3386/w17819>, Hummels, Ishii, and Yi (2001) <doi:10.1016/S0022-1996(00)00093-3>); across period analysis with impact analysis (Dietzenbacher, van der Linden, and Steenge (2006) <doi:10.1080/09535319300000017>, Sonis, Hewings, and Guo (2006) <doi:10.1080/09535319600000002>); and a variety of table operators.

The data analysis module for the Iterative Optimization Heuristics
    Profiler ('IOHprofiler'). This module provides statistical analysis methods for the 
    benchmark data generated by optimization heuristics, which can be visualized through a 
    web-based interface. The benchmark data is usually generated by the 
    experimentation module, called 'IOHexperimenter'. 'IOHanalyzer' also supports
    the widely used 'COCO' (Comparing Continuous Optimisers) data format for benchmarking.

Addresses the 'log of zero' by developing a new family of 
    estimators called iterated Ordinary Least Squares. 
    This family nests standard approaches such as log-linear and 
    Poisson regressions, offers several computational advantages, 
    and corresponds to the correct way to perform the popular 
    log(Y + 1) transformation. For more details about how to use it, 
    see the notebook at: <https://www.davidbenatia.com/>.

Method for the calculation of copy numbers and calling of copy number alterations. The algorithm uses coverage data from amplicon sequencing of a sample cohort as input. The method includes significance assessment, correction for multiple testing and does not depend on normal DNA controls. Budczies (2016 Mar 15) <doi:10.18632/oncotarget.7451>.