This 'Rcpp'-based package implements highly efficient functions for the calculation of the Jonckheere-Terpstra statistic. It can be used for a variety of applications, including feature selection in machine learning problems, or to conduct genome-wide association studies (GWAS) with multiple quantitative phenotypes. The code leverages 'OpenMP' directives for multi-core computing to reduce overall processing time.

A computationally efficient and statistically rigorous fast 
    Kernel Machine method for multi-kernel analysis. The approach is based on 
    a low-rank approximation to the nuisance effect kernel matrices. The 
    algorithm is applicable to continuous, binary, and survival traits and 
    is implemented using the existing single-kernel analysis software 'SKAT' 
    and 'coxKM'. 'coxKM' can be obtained from 
    <https://github.com/lin-lab/coxKM>.

R wrappers of C++ implementation of Faster K-Medoids clustering algorithms (FastPAM, FastCLARA and FastCLARANS) proposed in Erich Schubert, Peter J. Rousseeuw 2019 <doi:10.1007/978-3-030-32047-8_16>.

Compute labels for a test set according to the k-Nearest Neighbors classification. This is a fast way to do k-Nearest Neighbors classification because the distance matrix -between the features of the observations- is an input to the function rather than being calculated in the function itself every time.

An efficient algorithm to fit and tune kernel quantile regression models based on the majorization-minimization (MM) method. It can also fit multiple quantile curves simultaneously without crossing.

Provides core computational operations in C++ via 'RcppArmadillo', enabling faster performance than pure R, improved numerical stability, and parallel execution with OpenMP where available. On systems without OpenMP support, the package automatically falls back to single-threaded execution with no user configuration required. For efficient model selection, it integrates with 'CVST' to provide sequential-testing cross-validation that identifies competitive hyperparameters without exhaustive grid search. The package offers a unified interface for exact kernel ridge regression and three scalable approximations—Nyström, Pivoted Cholesky, and Random Fourier Features—allowing analyses with substantially larger sample sizes than are feasible with exact KRR. It also integrates with the 'tidymodels' ecosystem via the 'parsnip' model specification 'krr_reg', and the S3 method tunable.krr_reg(). To understand the theoretical background, one can refer to Wainwright (2019) <doi:10.1017/9781108627771>.