Wald Test for nonlinear restrictions on model parameters and confidence
             intervals for nonlinear functions  of parameters using delta-method.  Applicable
             after ANY model, provided parameters estimates and their covariance matrix are
             available.

Network meta-analysis tools based on contrast-based approach using the multivariate meta-analysis and meta-regression models (Noma et al. (2025) <doi:10.1101/2025.09.15.25335823>). Comprehensive analysis tools for network meta-analysis and meta-regression (e.g., synthesis analysis, ranking analysis, and creating league table) are available through simple commands. For inconsistency assessment, the local and global inconsistency tests based on the Higgins' design-by-treatment interaction model are available. In addition, the side-splitting methods and Jackson's random inconsistency model can be applied. Standard graphical tools for network meta-analysis, including network plots, ranked forest plots, and transitivity analyses, are also provided. For the synthesis analyses, the Noma-Hamura's improved REML (restricted maximum likelihood)-based methods (Noma et al. (2023) <doi:10.1002/jrsm.1652> <doi:10.1002/jrsm.1651>) are adopted as the default methods.

Implements HSROC (hierarchical summary receiver operating characteristic) model developed by Ma, Lian, Chu, Ibrahim, and Chen (2018) <doi:10.1093/biostatistics/kxx025> and hierarchical model developed by Lian, Hodges, and Chu (2019) <doi:10.1080/01621459.2018.1476239> for performing meta-analysis for 1-5 diagnostic tests to simultaneously compare multiple tests within a missing data framework. This package evaluates the accuracy of multiple diagnostic tests and also gives graphical representation of the results.

Provides customized forest plots for network meta-analysis incorporating direct, indirect, and NMA effects. Includes visualizations of evidence contributions through 
    proportion bars based on the hat matrix and evidence flow decomposition.