The Time-Delay Correlation algorithm (TDCor) reconstructs the topology of a gene regulatory network (GRN) from time-series transcriptomic data.  The algorithm is described in details in Lavenus et al., Plant Cell, 2015.  It was initially developed to infer the topology of the GRN controlling lateral root formation in Arabidopsis thaliana.  The time-series transcriptomic dataset which was used in this study is included in the package to illustrate how to use it.

The total deviation index (TDI) is an unscaled statistical measure used to evaluate the deviation between paired quantitative measurements when assessing the extent of agreement between different raters. It describes a boundary such that a large specified proportion of the differences in paired measurements are within the boundary (Lin, 2000) <https://pubmed.ncbi.nlm.nih.gov/10641028/>.
    This R package implements some methodologies existing in the literature for TDI estimation and inference in the case of two raters.

The t-Digest construction algorithm, by 
    Dunning et al., (2019) <doi:10.48550/arXiv.1902.04023>, uses a variant of 1-dimensional 
    k-means clustering to produce a very compact data structure that allows 
    accurate estimation of quantiles. This t-Digest data structure can be used 
    to estimate quantiles, compute other rank statistics or even to estimate 
    related measures like trimmed means. The advantage of the t-Digest over 
    previous digests for this purpose is that the t-Digest handles data with 
    full floating point resolution. The accuracy of quantile estimates produced 
    by t-Digests can be orders of magnitude more accurate than those produced 
    by previous digest algorithms. Methods are provided to create and update 
    t-Digests and retrieve quantiles from the accumulated distributions.

The main purpose of this package is to propose a rigorous framework to fairly compare trip distribution laws and models as described in Lenormand et al. (2016) <doi:10.1016/j.jtrangeo.2015.12.008>.