Calculate the statistical power to detect clusters using kernel-based 
        spatial relative risk functions that are estimated using the 'sparr' package.
        Details about the 'sparr' package methods can be found in the tutorial: Davies
        et al. (2018) <doi:10.1002/sim.7577>. Details about kernel density estimation 
        can be found in J. F. Bithell (1990) <doi:10.1002/sim.4780090616>. More 
        information about relative risk functions using kernel density estimation can 
        be found in J. F. Bithell (1991) <doi:10.1002/sim.4780101112>.

The 'HJ-Biplot' is a multivariate method that represents high-dimensional data in a low-dimensional subspace, capturing most of the information’s variability in just a few dimensions. This package implements three new regularized versions of the HJ-Biplot: Ridge, LASSO, and Elastic Net. These versions introduce restrictions that shrink or zero-out variable weights to improve interpretability based on regularization theory. All methods provide graphical representations using 'ggplot2'.

'C++' classes for sparse matrix methods including implementation of sparse LDL decomposition of symmetric matrices and solvers described by Timothy A. Davis (2016) 
  <https://fossies.org/linux/SuiteSparse/LDL/Doc/ldl_userguide.pdf>. Provides a set of C++ classes for basic sparse
  matrix specification and linear algebra, and a class to implement sparse LDL decomposition and solvers. See <https://github.com/samuel-watson/SparseChol>
  for details.

A sparse covariance estimator based on different thresholding operators.

Implements the algorithm described in 
    Barron, M., Zhang, S. and Li, J. 2017, "A sparse differential
    clustering algorithm for tracing cell type changes via single-cell
    RNA-sequencing data", Nucleic Acids Research, gkx1113,
    <doi:10.1093/nar/gkx1113>. This algorithm clusters samples from two
    different populations, links the clusters across the conditions and
    identifies marker genes for these changes. The package was designed for
    scRNA-Seq data but is also applicable to many other data types, just
    replace cells with samples and genes with variables. The package also
    contains functions for estimating the parameters for SparseDC as outlined
    in the paper. We recommend that users further select their marker genes
    using the magnitude of the cluster centers.