Dose          R1    R2    R3 Sample

Dose-0.010 0.633 0.629 0.649 S
Dose-0.020 0.401 0.409 0.411 S
Dose-0.040 0.206 0.204 0.211 S
Dose-0.080 0.077 0.079 0.080 S
Dose-0.010 0.502 0.508 0.518 T
Dose-0.020 0.297 0.29  0.302 T
Dose-0.040 0.136 0.128 0.136 T
Dose-0.080 0.040 0.042 0.035 T

Model                    . . . "Parallel lines"
Design                   . . . "Completely randomised"
Transformation           . . . "y' = sqrt(y)"
FUN                      . . . "function(x) sqrt(x)"
INV                      . . . "function(x) x^2"
Factor                   . . . "600, 100, 100 / 1.42076439"
Rows                     . . . "Dilutions & Samples"
Columns                  . . . "Replicates"
DilutionRatio            . . . "2"

ResultOfAssay            . . . "Example 8: Human Hepatitis A immunoglobulin"
Project                  . . . "CombiStats - EDQM, Council of Europe"
Description              . . . "Four-dose parallel line assay; explicit content notation"
Comment                  . . . "Square root transformation"
Resume                   . . . ""
Date                     . . . ""
Operator                 . . . ""

Source                   . . . "CombiStats - EDQM, Council of Europe"
URL                      . . . "http://combistats.edqm.eu/images/stories/Examples/Hepatitis%20A%20Ig.pdf"
Example                  . . . "08"
Substance                . . . "Human Hepatitis A immunoglobulin"
Method                   . . . "Elisa"

StandardSample           . . . "Sample Ph. Eur. BRP Batch 1"
StandardAssPot           . . . "10.2 IU/vial"
StandardReconstitution   . . . "1 vial / ml"
StandardDilutions        . . . "0.080 0.040 0.020 0.010"

Sample1Sample            . . . "Batch 35K09755"
Sample1AssPot            . . . "600 IU/ampoule"
Sample1Reconstitution    . . . "1 ampoule / ml"
Sample1Dilutions         . . . "0.080 0.040 0.020 0.010"

A1@Preparations          1    0.0462082      0.0462082    >1000    
A1@Regression            1    0.900001       0.900001     >1000    
A1@Non-parallelism       1    4.46096E-06    4.46096E-06      0.131    
A1@Non-linearity         4    0.000372149    9.30372E-05      2.734    
A1@_Standard             2    0.000301770    0.000150885      4.433    
A1@_Sample1              2    7.03791E-05    3.51896E-05      1.034    
A1@Quadratic_curvature   1    6.14615E-05    6.14615E-05      1.806    
A1@Lack_of_quadratic_fit 3    0.000310687    0.000103562      3.043    
A1@Treatments            7    0.946586       0.135227     >1000    
A1@Residual_error       16    0.000544535    3.40335E-05       .    
A1@Total                23    0.947131       0.0411796         .    
P1@Potency               .  835.028        852.459          870.357    
P1@ReltoAss              .  139.2          142.1            145.1    
P1@ReltoEst              .   98.0          100.0            102.1    
C1@CommonSlope(factor)   .   -0.249882        .                .    
C1@Correlation           .    0.999514        .                .    
             
A2@Preparations          0.000 . . ""
A2@Regression            0.000 . . ""
A2@Non-parallelism       0.722 . . ""
A2@Non-linearity         0.066 . . ""
A2@Standard              0.029 . . ""
A2@Sample1               0.378 . . ""
A2@Quadraticcurvature    0.198 . . ""
A2@Lackofquadraticfit    0.059 . . ""
A2@Treatments            0.000 . . ""
A2@Residualerror         .     . . ""
A2@Total                 .     . . ""
P2@Potency               .     . . ""
P2@ReltoAss              .     . . ""
P2@ReltoEst              .     . . ""
C2@CommonSlope(factor)   .     . . ""
C2@Correlation           .     . . ""
                 

